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Prescription treatment is subject to clinical review. Availability and eligibility vary.

Apexa by Cedra Healthcare
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WellnessPain ManagementLow Dose Naltrexone
Low Dose
Provider-guided care

Low Dose Naltrexone

$33.33/ month · capsule
Available plans
Start a free assessment

Treatment and plan are confirmed after your assessment.

Care starts with a clinician review

A licensed provider reviews your health history and determines whether treatment is appropriate for you.

What Is Low Dose Naltrexone?

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How Low Dose Naltrexone works

Reviewing Apexa care options on a laptop at homeStep 01

Modulates Immune System Function

Low Dose Naltrexone works by briefly blocking your body's opioid receptors for approximately 4-6 hours, typically during sleep. This temporary blockade creates a rebound effect that prompts your body to increase production of endorphins and enkephalins—your natural feel-good chemicals. These naturally occurring substances help regulate immune function and reduce inflammation throughout your body.

A clinician reviewing care information on a laptopStep 02

Regulates Inflammatory Response

At low doses (typically 1.5-4.5 mg), naltrexone acts on specialized immune cells called microglia and helps regulate inflammatory pathways in your body. Unlike higher doses used for addiction treatment, low dose naltrexone specifically targets Toll-like Receptor 4 (TLR-4), helping to decrease the production of pro-inflammatory chemicals called cytokines. This balanced immune response may help reduce chronic inflammation associated with autoimmune conditions and chronic pain.

Opening an Apexa treatment package at homeStep 03

Promotes Natural Healing Processes

With consistent daily use, Low Dose Naltrexone helps restore your body's natural balance by supporting healthy endorphin levels throughout the day. This sustained improvement in your body's own regulatory systems can lead to better tissue repair, improved sleep quality, reduced pain sensitivity, and enhanced overall well-being. Most patients begin noticing benefits within 2-3 months as these cumulative effects build, though some may experience improvements sooner.

How to get Low Dose Naltrexone online

From your first assessment to the next step in your care.

Opening an Apexa care package at home
  1. 01. Tell us about you

    Complete an online assessment about your goals, health history, and current routine.

  2. 02. Connect with a provider

    A licensed provider reviews your information and determines whether treatment is appropriate for you.

  3. 03. Begin care, if prescribed

    Review your treatment plan and use your patient account to manage consultations, orders, and messages.

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Learn more about this treatment and what to expect from your care.