Step 01Step 1: Topical Application & Absorption
When you apply the testosterone and estradiol cream to your skin as directed, the hormones begin to absorb through the outer layers. The cream is formulated to allow these bioidentical hormones to pass through the skin barrier and enter the bloodstream. Clean, dry skin in areas with good blood flow (such as inner arms, thighs, or abdomen) provides optimal absorption. The lipophilic nature of these hormones allows them to dissolve through the skin's lipid layers efficiently.



