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Prescription treatment is subject to clinical review. Availability and eligibility vary.

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For WomenWomen's HealthEstradiol Cream
Estradiol Cream
Provider-guided care

Estradiol Cream

$55/ month · cream
Available plans
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Treatment and plan are confirmed after your assessment.

Care starts with a clinician review

A licensed provider reviews your health history and determines whether treatment is appropriate for you.

What Is Estradiol Cream?

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How Estradiol Cream works

Reviewing Apexa care options on a laptop at homeStep 01

Step 1: Application and Absorption

When you apply the estradiol cream to your skin as directed, the bioidentical estrogen hormone is absorbed directly through the skin's layers into your bloodstream. This topical delivery method allows the medication to bypass the digestive system, providing a steady, controlled release of estradiol into your body.

A clinician reviewing care information on a laptopStep 02

Step 2: Hormone Replacement

Once absorbed, estradiol circulates through your bloodstream and binds to estrogen receptors throughout your body. This bioidentical hormone works exactly like your body's natural estrogen, helping to restore hormone levels that may have declined due to menopause or other conditions. The supplemented estrogen helps regulate various bodily functions that depend on adequate estrogen levels.

Opening an Apexa treatment package at homeStep 03

Step 3: Symptom Relief

As estradiol levels stabilize in your system, you may experience relief from symptoms associated with low estrogen, such as hot flashes, vaginal dryness, night sweats, and mood changes. The hormone works to restore balance to affected tissues and systems, including vaginal and urinary tract tissues, bone density regulation, and temperature control mechanisms, helping you feel more comfortable and improving your quality of life.

How to get Estradiol Cream online

From your first assessment to the next step in your care.

Opening an Apexa care package at home
  1. 01. Tell us about you

    Complete an online assessment about your goals, health history, and current routine.

  2. 02. Connect with a provider

    A licensed provider reviews your information and determines whether treatment is appropriate for you.

  3. 03. Begin care, if prescribed

    Review your treatment plan and use your patient account to manage consultations, orders, and messages.

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Learn more about this treatment and what to expect from your care.